Please join us for the Annual Centre for Medical & Industrial Ultrasonics Dugald Cameron Lecture, given this year by Dr. Kullervo Hynynen. Dr. Kullervo Hynynen is Vice-President, Research and Innovation Senior Scientist at Sunnybrook Health Science Centre (Toronto). This will take place in the Sir Charles Wilson Building Lecture Theatre, University of Glasgow on Tuesday 15th April at 15:30.

Agenda: 
15:30-16:15- Assembly, registration, networking over tea and coffee
16:15-16:30- Prof. Margaret Lucas- C-MIU Introduction & Prof. Sandy Cochran - FUSE CDT Introduction
16:30-17:30- Dr. Kullervo Hynynen, guest speaker giving the Dugald Cameron lecture followed by Q&A
17:30-19:00- Evening reception (Drinks/ canapés)

Presentation Title: Trans-skull MRI-guided focused ultrasound – From an idea to clinical practice and beyond.

Presentation Abstract :When combined with MRI-guided focused ultrasound (FUS), this technology offers a precise means of delivering localized mechanical energy to specific anatomical or physiological targets deep within the body. This focal energy deposition can modify tissue function through thermal or mechanical interactions with the tissue. This approach is particularly advantageous in the brain, where tissue penetration could potentially damage critical functions. The ability to directly target tissue without affecting the surrounding structures offers significant benefits. In this presentation, we will review the key advancements that led to clinical trials and the use of focused ultrasound ablation for tremor treatment, as well as the clinical trials focused on ultrasound-enhanced blood-brain barrier permeability for image-guided drug delivery. We will also explore the potential applications of neuromodulation and sonodynamic therapy. Finally, an overview of the current state of focused ultrasound technology will be provided, along with a discussion on its clinical potential.

Guest Speaker's Biography: Dr. Hynynen earned his Ph.D. from the University of Aberdeen in the United Kingdom and began his academic career as a faculty member at the University of Arizona. In 1993, he joined the faculty of Harvard University and Brigham and Women's Hospital in Boston. In 2006, Dr. Hynynen was appointed Senior Scientist and Director of the Physical Sciences Platform at Sunnybrook Research Institute. He assumed the role of Vice President of Research and Innovation at Sunnybrook, Toronto, Canada in January 2020. Dr. Hynynen is a Professor in the Department of Medical Biophysics at the University of Toronto, with a cross-appointment in the Institute of Biomedical Engineering (BME). He holds the Temerty Chair in Focused Ultrasound Research and serves as Co-Director of the Focused Ultrasound Centre of Excellence at Sunnybrook Health Sciences Centre. Dr. Hynynen is also the founder and Co-Executive Director of INOVAIT, a nationwide network focused on advancing the use of artificial intelligence in image-guided therapy through training, networking, and funding. With over 450 peer-reviewed publications in the field of ultrasound therapy, he is internationally recognized as a leader in both basic and clinical research. He holds approximately 30 patents or patent applications and has been awarded numerous research grants and contracts. His intellectual property has been licensed by several companies, including two he founded. Notably, the focused ultrasound technology developed by InSightec, now in clinical use for essential tremor treatments, originated from Dr. Hynynen's laboratory.